Volatile oils as Alternative Medicine to Treat Abscess Infection Caused by Multidrug-Resistant bacteria

Abstract

Background  and Objective: Volatile oils (1- Eucalyptus, 2- Chamomile, 3- Peppermint, 4- Marjoram, 5- Fennel, 6- Spearmint) have antimicrobial activity against bacteria were used. This study aim to find alternative natural products and increase the effectiveness of antibiotics by combination with some of these products to eliminate resistant bacteria. Spearmint oil, will aid pharmaceutical companies in creating new antibiotics that are used to treat illnesses brought on by bacteria that are resistant to pathogens.
Methods: Seventy two swabs from clinical samples of abscesses. All isolates were determined by Bergey's Manual of Determinative Bacteriology and various antibiotics were utilized during the experiment. Volatile oils were used and tested against clinical bacterial isolates.
Results: 72.2% of the isolates of abscesses are S. aureus, while 27.8% of the Gram-negative isolates include P. vulgaris, P. aeruginosae, and E. coli.  Norfloxacin has a 61.2% sensitivity to isolated pathogenic bacteria, followed by chloramphenicol and amikacin. However, the pathogenic bacteria that have been isolated are completely resistant to cefoperazone and penicillin, The antibiotics norfloxacin (31.25 µg/ml) and chloramphenicol (31.25 µg/ml) were shown to have the lowest minimum inhibitory concentrations (MIC) against S. aureus 18, 59, and 70, and S. aureus 58, respectively, no significant difference was observed between norfloxacin and chloramphenicol (p > 0.05). Fennel and spearmint oils showed significant antagonistic activity and chamomile oil have no antagonistic effect, significant difference was observed between spearmint and fennel (p < 0.05) Combination between norfloxacin and spearmint oil were found to have a synergistic impact against E. coli number 9 and S. aureus numbers 5, 18, and 47.
Conclusion:  In addition to offering ongoing protection against bacteria resistant to antibiotics, the variety of volatile oils and their efficacy offer fresh hope for the treatment of abscesses.
Keywords: Antibiotic Resistance, Abscesses, Volatile oils.